Roller-type blister packing machine seals and packages blisters by aluminum/plastic (PTP/PVC) for medicines (tablets or capsules), food, health products, electronic components and other similar products. Positive pressure forming and platen heat sealing produces flat and neat blisters with full and smooth pockets. The speed of 180 punches per minute is roughly 4 to 5 times of other ordinary blister machines. The machine integrates the advantages of both flat-type and roller-type blister machines, configured with a special tablet feeder (or an automatic capsule U-turn reorientation device), characteristic of high punch frequency, low energy consumption, accurate and stable process, easy format changeover and high yield, especially adaptive to blisters, thus resulting in great improvement of production efficiency.